These experimental in vitro findings had been confirmed working with human clinical samples, which unveiled that the stroma of OSF contained myofibroblasts and that TGF-b1-dependent Smad signaling was detectable both in keratinocytes and in myofibroblasts
AKT/protein kinase B (PKB) is a serine/threonine kinase which is implicated in mediating a wide variety of biological responses such as cell growth, proliferation and survival. AKT is activated by…