Initial of all, at present there is no appropriate technique to purify native MASP-1 from plasma or serum and as a result numerous attempts to purify MASP-1 in ample quantities and free from contamination with other MASPs have unsuccessful
The vital role of prothrombin is supported by our knowledge demonstrating the inability of MASP-one to induce fibrin clot development in PT-DP in the turbidimetric assay, and the capability of…