Product Name :
AZ-628
CAS No.:
878739-06-1
Purity :
> 98%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
CN1C=NC2=C(C=C(NC3=CC(=CC=C3C)NC(=O)C4=CC(=CC=C4)C(C)(C)C#N)C=C2)C1=O
Product Description :
AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 nM, 34 nM and 29 nM in cell-free assays, also inhibits VEGFR2, DDR2, Lyn, Flt1, FMS, etc.{{11089-65-9} medchemexpress|{11089-65-9} Biological Activity|{11089-65-9} Data Sheet|{11089-65-9} supplier}
Formula:
C27H25N5O2
Molecular Weight :
451.{{1945950-21-9} medchemexpress|{1945950-21-9} Protocol|{1945950-21-9} Formula|{1945950-21-9} custom synthesis} 52
Synonyms:
Additional Information:
|CAS No.PMID:30422487 878739-06-1 ; |Formula C27H25N5O2 ; |Molecular Weight 451.52 ; |SMILES CN1C=NC2=C(C=C(NC3=CC(=CC=C3C)NC(=O)C4=CC(=CC=C4)C(C)(C)C#N)C=C2)C1=O ; |Product Description AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 nM, 34 nM and 29 nM in cell-free assays, also inhibits VEGFR2, DDR2, Lyn, Flt1, FMS, etc. ; |Purity > 98% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO