Product Name :
S29434
Description:
S29434 (NMDPEF) is a potent, competitive, selective and cell-permeable inhibitor of quinone reductase 2 (QR2), with IC50s ranging from 5 to 16 nM for human QR2 at different organizational levels, and has good selectivity for QR2 over QR1. S29434 (NMDPEF) induces autophagy and inhibits QR2-mediated ROS production.
CAS:
874484-20-5
Molecular Weight:
374.39
Formula:
C21H18N4O3
Chemical Name:
N-(2-{5-methoxy-1,6,11-triazatetracyclo[7.7.0.0²,⁷.0¹⁰,¹⁵]hexadeca-2,4,6,8,10,12,14-heptaen-8-yl}ethyl)furan-2-carboxamide
Smiles :
COC1=CC=C2C(=N1)C(CCNC(=O)C1=CC=CO1)=C1C3=NC=CC=C3CN12
InChiKey:
XJIUMLVQBQKCJA-UHFFFAOYSA-N
InChi :
InChI=1S/C21H18N4O3/c1-27-17-7-6-15-19(24-17)14(8-10-23-21(26)16-5-3-11-28-16)20-18-13(12-25(15)20)4-2-9-22-18/h2-7,9,11H,8,10,12H2,1H3,(H,23,26)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Teriflunomide} site|{Teriflunomide} Metabolic Enzyme/Protease|{Teriflunomide} Technical Information|{Teriflunomide} Data Sheet|{Teriflunomide} supplier|{Teriflunomide} Epigenetics}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
S29434 (NMDPEF) is a potent, competitive, selective and cell-permeable inhibitor of quinone reductase 2 (QR2), with IC50s ranging from 5 to 16 nM for human QR2 at different organizational levels, and has good selectivity for QR2 over QR1.{{Ondansetron} site|{Ondansetron} 5-HT Receptor|{Ondansetron} Purity & Documentation|{Ondansetron} In Vitro|{Ondansetron} supplier|{Ondansetron} Cancer} S29434 (NMDPEF) induces autophagy and inhibits QR2-mediated ROS production.PMID:23865629 |Product information|CAS Number: 874484-20-5|Molecular Weight: 374.39|Formula: C21H18N4O3|Chemical Name: N-(2-{5-methoxy-1,6,11-triazatetracyclo[7.7.0.0²,⁷.0¹⁰,¹⁵]hexadeca-2,4,6,8,10,12,14-heptaen-8-yl}ethyl)furan-2-carboxamide|Smiles: COC1=CC=C2C(=N1)C(CCNC(=O)C1=CC=CO1)=C1C3=NC=CC=C3CN12|InChiKey: XJIUMLVQBQKCJA-UHFFFAOYSA-N|InChi: InChI=1S/C21H18N4O3/c1-27-17-7-6-15-19(24-17)14(8-10-23-21(26)16-5-3-11-28-16)20-18-13(12-25(15)20)4-2-9-22-18/h2-7,9,11H,8,10,12H2,1H3,(H,23,26)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 19.29 mg/mL (51.52 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|