Product Name :
ODM-203
Description:
ODM-203 is a potent FGFR and VEGFR families inhibitor with IC50s of 11, 16, 6, 35 nM towards recombinant FGFR1, FGFR2, FGFR3 and FGFR4 as well as 26, 9, 5 nM towards VEGFR1, VEGFR2 and VEGFR3, respectively. ODM-203 exhibits strong anti-tumor activity and induces anti-tumor immunity.
CAS:
1430723-35-5
Molecular Weight:
505.54
Formula:
C26H21F2N5O2S
Chemical Name:
N-{2′,4′-difluoro-5-[5-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-1-yl]-[1,1′-biphenyl]-3-yl}cyclopropanesulfonamide
Smiles :
CN1C=C(C=N1)C1C=C2N=CN(C3=CC(=CC(=C3)NS(=O)(=O)C3CC3)C3=CC=C(F)C=C3F)C2=CC=1
InChiKey:
ZJFCBQXPTQSTCZ-UHFFFAOYSA-N
InChi :
InChI=1S/C26H21F2N5O2S/c1-32-14-18(13-30-32)16-2-7-26-25(10-16)29-15-33(26)21-9-17(23-6-3-19(27)11-24(23)28)8-20(12-21)31-36(34,35)22-4-5-22/h2-3,6-15,22,31H,4-5H2,1H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Amiloride hydrochloride dihydrate} site|{Amiloride hydrochloride dihydrate} Membrane Transporter/Ion Channel|{Amiloride hydrochloride dihydrate} Immunology/Inflammation|{Amiloride hydrochloride dihydrate} Technical Information|{Amiloride hydrochloride dihydrate} In Vitro|{Amiloride hydrochloride dihydrate} supplier}
Additional information:
ODM-203 is a potent FGFR and VEGFR families inhibitor with IC50s of 11, 16, 6, 35 nM towards recombinant FGFR1, FGFR2, FGFR3 and FGFR4 as well as 26, 9, 5 nM towards VEGFR1, VEGFR2 and VEGFR3, respectively. ODM-203 exhibits strong anti-tumor activity and induces anti-tumor immunity.|Product information|CAS Number: 1430723-35-5|Molecular Weight: 505.54|Formula: C26H21F2N5O2S|Chemical Name: N-{2′,4′-difluoro-5-[5-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-1-yl]-[1,1′-biphenyl]-3-yl}cyclopropanesulfonamide|Smiles: CN1C=C(C=N1)C1C=C2N=CN(C3=CC(=CC(=C3)NS(=O)(=O)C3CC3)C3=CC=C(F)C=C3F)C2=CC=1|InChiKey: ZJFCBQXPTQSTCZ-UHFFFAOYSA-N|InChi: InChI=1S/C26H21F2N5O2S/c1-32-14-18(13-30-32)16-2-7-26-25(10-16)29-15-33(26)21-9-17(23-6-3-19(27)11-24(23)28)8-20(12-21)31-36(34,35)22-4-5-22/h2-3,6-15,22,31H,4-5H2,1H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 66.{{Dizocilpine} web|{Dizocilpine} Neuronal Signaling|{Dizocilpine} NF-κB|{Dizocilpine} Technical Information|{Dizocilpine} In Vitro|{Dizocilpine} supplier} 67 mg/mL (131.PMID:23329650 88 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|