December, 2024 | Folate-Analogue folate-analogue.com

Trichodesmine

Folate Analogue December 31, 2024 0 Comments

Product Name : TrichodesmineDescription:Trichodesmine is a dehydropyrrolizidine alkaloid. Trichodesmine can produces hepatotoxicty, pneumo- and neurotoxicity in vivo.CAS: 548-90-3Molecular Weight:353.41Formula: C18H27NO6Chemical Name: (1R,4R,5R,6R,16R)-5,6-dihydroxy-5,6-dimethyl-4-(propan-2-yl)-2,8-dioxa-13-azatricyclohexadec-10-ene-3,7-dioneSmiles : CC(C)1C(=O)O2CCN3CC=C(COC(=O)(C)(O)1(C)O)32InChiKey: SOODLZHDDSGRKL-FOOXYVKASA-NInChi : InChI=1S/C18H27NO6/c1-10(2)13-15(20)25-12-6-8-19-7-5-11(14(12)19)9-24-16(21)18(4,23)17(13,3)22/h5,10,12-14,22-23H,6-9H2,1-4H3/t12-,13+,14-,17-,18+/m1/s1Purity: ≥98% (or refer…

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Indomethacin sodium hydrate

Folate Analogue December 30, 2024 0 Comments

Product Name : Indomethacin sodium hydrateDescription:Indomethacin sodium hydrate (Indometacin sodium hydrate) is a potent, blood-brain permeable and nonselective inhibitor of COX1 and COX2, with IC50s of 18 nM and 26…

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MC-Val-Cit-PAB-vinblastine

Folate Analogue December 29, 2024 0 Comments

Product Name : MC-Val-Cit-PAB-vinblastineDescription:MC-Val-Cit-PAB-vinblastine is a drug-linker conjugate for ADC with potent antitumor activity by using vinblastine (an microtubule protein inhibitor), linked via the ADC linker MC-Val-Cit-PAB.CAS: 2055896-92-7Molecular Weight:1366.62Formula: C74H97N10O15Chemical…

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(S)-Rasagiline

Folate Analogue December 28, 2024 0 Comments

Product Name : (S)-RasagilineDescription:(S)-Rasagiline (TVP1022) is the relatively inactive S-enantiomer form of Rasagiline. Rasagiline is a highly potent selective irreversible MAO inhibitor with IC50s of 4.43 nM and 412 nM for rat…

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TLR7 agonist 3

Folate Analogue December 27, 2024 0 Comments

Product Name : TLR7 agonist 3Description:TLR7 agonist 3 (Compound 2) is a potent agonist of toll-like receptor 7 (TLR7). TLR7 has an important role in immune activation processes and represents…

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Oxcarbazepine

Folate Analogue December 26, 2024 0 Comments

Product Name : OxcarbazepineDescription:Oxcarbazepine is an anticonvulsant drug primarily used in the treatment of epilepsy. There is some evidence for oxcarbazepine as a mood-stabilizing agent and thus, it can be…

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Ketanserin

Folate Analogue December 25, 2024 0 Comments

Product Name : KetanserinDescription:Ketanserin is a selective 5-HT2 receptor antagonist. Ketanserin also blocks hERG current (IhERG) in a concentration-dependent manner (IC50=0.11 μM).CAS: 74050-98-9Molecular Weight:395.43Formula: C22H22FN3O3Chemical Name: 3-{2-ethyl}-1, 2, 3, 4-tetrahydroquinazoline-2,…

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Puromycin aminonucleoside

Folate Analogue December 24, 2024 0 Comments

Product Name : Puromycin aminonucleosideDescription:Puromycin aminonucleoside (NSC 3056, PAN, Stylomycin aminonucleoside, ARDMA, SAN), the aminonucleoside portion of the antibiotic puromycin, is a reversible inhibitor of dipeptidyl-peptidase II and cytosol alanyl…

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PF-04995274

Folate Analogue December 23, 2024 0 Comments

Product Name : PF-04995274Description:PF-04995274 (PF-4995274) is a potent, high-affinity, orally active and partial agonist of serotonin 4 receptor (5-HT4R) with EC50 of 0.47 nM, 0.36 nM, 0.37 nM and 0.26…

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AT-56

Folate Analogue December 23, 2024 0 Comments

Product Name : AT-56Description:AT-56 is an orally active and selective inhibitor of lipocalin-type prostaglandin (PG) D synthase (L-PGDS) with Ki of 75 μM and IC50 of 95 μM.CAS: 162640-98-4Molecular Weight:397.52Formula:…

Trichodesmine

Indomethacin sodium hydrate

MC-Val-Cit-PAB-vinblastine

(S)-Rasagiline

TLR7 agonist 3

Oxcarbazepine

Ketanserin

Puromycin aminonucleoside

PF-04995274

AT-56

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