Product Name :
8-M-PDOT
Description:
8-M-PDOT (AH-002) is a selective melatonin MT2 receptor agonist. 8-M-PDOT is 5.2-fold selective for MT2 over MT1 receptors. 8-M-PDOT binds human recombinant MT2 and MT2 receptors with pKi values of 8.23 and 8.95 respectively. 8-M-PDOT has anxiolytic-like activity.
CAS:
134865-70-6
Molecular Weight:
233.31
Formula:
C14H19NO2
Chemical Name:
N-(8-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)propanamide
Smiles :
CCC(=O)NC1CC2C(=CC=CC=2CC1)OC
InChiKey:
RVIGBTUDFAGRTQ-UHFFFAOYSA-N
InChi :
InChI=1S/C14H19NO2/c1-3-14(16)15-11-8-7-10-5-4-6-13(17-2)12(10)9-11/h4-6,11H,3,7-9H2,1-2H3,(H,15,16)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
8-M-PDOT (AH-002) is a selective melatonin MT2 receptor agonist. 8-M-PDOT is 5.2-fold selective for MT2 over MT1 receptors. 8-M-PDOT binds human recombinant MT2 and MT2 receptors with pKi values of 8.23 and 8.95 respectively. 8-M-PDOT has anxiolytic-like activity.|Product information|CAS Number: 134865-70-6|Molecular Weight: 233.{{Olodaterol} medchemexpress|{Olodaterol} GPCR/G Protein|{Olodaterol} Technical Information|{Olodaterol} Data Sheet|{Olodaterol} supplier|{Olodaterol} Cancer} 31|Formula: C14H19NO2|Chemical Name: N-(8-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)propanamide|Smiles: CCC(=O)NC1CC2C(=CC=CC=2CC1)OC|InChiKey: RVIGBTUDFAGRTQ-UHFFFAOYSA-N|InChi: InChI=1S/C14H19NO2/c1-3-14(16)15-11-8-7-10-5-4-6-13(17-2)12(10)9-11/h4-6,11H,3,7-9H2,1-2H3,(H,15,16)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 100 mg/mL (428.{{Givosiran} MedChemExpress|{Givosiran} Small Interfering RNA (siRNA)|{Givosiran} Protocol|{Givosiran} In stock|{Givosiran} manufacturer|{Givosiran} Autophagy} 61 mM; Need ultrasonic).PMID:24179643 |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|8-M-PDOT (10 µg/µL; administrated into the dorsal striatum by bilateral cannulas; for 30 minutes; male Wistar rats) treatment shows anxiolytic-like effect.|Products are for research use only. Not for human use.|