Product Name :
GAP-134
Description:
Danegaptide, also known as GAP-134 and ZP1609, is an orally active small molecule gap-junction modifier for the treatment of atrial fibrillation. Danegaptide mproves conduction and reduces atrial fibrillation/flutter in the canine sterile pericarditis model. Danegaptide prevents spontaneous ventricular arrhythmias and reduces infarct size during myocardial ischemia/reperfusion injury in open-chest dogs.
CAS:
943134-39-2
Molecular Weight:
291.30
Formula:
C14H17N3O4
Chemical Name:
(2S,4R)-1-(2-aminoacetyl)-4-benzamidopyrrolidine-2-carboxylic acid
Smiles :
NCC(=O)N1C[C@@H](C[C@H]1C(O)=O)NC(=O)C1C=CC=CC=1
InChiKey:
BIZKIHUJGMSVFD-MNOVXSKESA-N
InChi :
InChI=1S/C14H17N3O4/c15-7-12(18)17-8-10(6-11(17)14(20)21)16-13(19)9-4-2-1-3-5-9/h1-5,10-11H,6-8,15H2,(H,16,19)(H,20,21)/t10-,11+/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Doxycycline} site|{Doxycycline} Bacterial|{Doxycycline} Technical Information|{Doxycycline} In Vitro|{Doxycycline} custom synthesis|{Doxycycline} Autophagy}
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Danegaptide, also known as GAP-134 and ZP1609, is an orally active small molecule gap-junction modifier for the treatment of atrial fibrillation. Danegaptide mproves conduction and reduces atrial fibrillation/flutter in the canine sterile pericarditis model. Danegaptide prevents spontaneous ventricular arrhythmias and reduces infarct size during myocardial ischemia/reperfusion injury in open-chest dogs.|Product information|CAS Number: 943134-39-2|Molecular Weight: 291.30|Formula: C14H17N3O4|Chemical Name: (2S,4R)-1-(2-aminoacetyl)-4-benzamidopyrrolidine-2-carboxylic acid|Smiles: NCC(=O)N1C[C@@H](C[C@H]1C(O)=O)NC(=O)C1C=CC=CC=1|InChiKey: BIZKIHUJGMSVFD-MNOVXSKESA-N|InChi: InChI=1S/C14H17N3O4/c15-7-12(18)17-8-10(6-11(17)14(20)21)16-13(19)9-4-2-1-3-5-9/h1-5,10-11H,6-8,15H2,(H,16,19)(H,20,21)/t10-,11+/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Calcein} MedChemExpress|{Calcein} {Fluorescent Dye}|{Calcein} Technical Information|{Calcein} In Vivo|{Calcein} manufacturer|{Calcein} Autophagy} |Shelf Life: ≥360 days if stored properly.PMID:26446225 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|