Product Name :
FLT3-IN-4
Description:
FLT3-IN-4 is a potent and orally effective Fms-like tyrosine receptor kinase 3 (FLT3; IC50=7 nM) inhibitor for treating acute myelogenous leukemia.
CAS:
2304799-09-3
Molecular Weight:
431.49
Formula:
C23H25N7O2
Chemical Name:
1-{4-[4-amino-7-(prop-2-en-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl}-3-(5-tert-butyl-1,2-oxazol-3-yl)urea
Smiles :
CC(C)(C)C1=CC(NC(=O)NC2C=CC(=CC=2)C2=CN(CC=C)C3=NC=NC(N)=C23)=NO1
InChiKey:
XIMGYPHSYIMHAW-UHFFFAOYSA-N
InChi :
InChI=1S/C23H25N7O2/c1-5-10-30-12-16(19-20(24)25-13-26-21(19)30)14-6-8-15(9-7-14)27-22(31)28-18-11-17(32-29-18)23(2,3)4/h5-9,11-13H,1,10H2,2-4H3,(H2,24,25,26)(H2,27,28,29,31)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Tegoprazan} site|{Tegoprazan} Potassium Channel|{Tegoprazan} Biological Activity|{Tegoprazan} In Vitro|{Tegoprazan} custom synthesis|{Tegoprazan} Epigenetics}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
FLT3-IN-4 is a potent and orally effective Fms-like tyrosine receptor kinase 3 (FLT3; IC50=7 nM) inhibitor for treating acute myelogenous leukemia.|Product information|CAS Number: 2304799-09-3|Molecular Weight: 431.49|Formula: C23H25N7O2|Chemical Name: 1-{4-[4-amino-7-(prop-2-en-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl}-3-(5-tert-butyl-1,2-oxazol-3-yl)urea|Smiles: CC(C)(C)C1=CC(NC(=O)NC2C=CC(=CC=2)C2=CN(CC=C)C3=NC=NC(N)=C23)=NO1|InChiKey: XIMGYPHSYIMHAW-UHFFFAOYSA-N|InChi: InChI=1S/C23H25N7O2/c1-5-10-30-12-16(19-20(24)25-13-26-21(19)30)14-6-8-15(9-7-14)27-22(31)28-18-11-17(32-29-18)23(2,3)4/h5-9,11-13H,1,10H2,2-4H3,(H2,24,25,26)(H2,27,28,29,31)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{DPH} web|{DPH} Bcr-Abl|{DPH} Purity & Documentation|{DPH} References|{DPH} supplier|{DPH} Epigenetic Reader Domain} |Shelf Life: ≥12 months if stored properly.PMID:23880095 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|FLT3-IN-4 (Compound 9u) shows potent inhibitory activities against MV4-11 and Molm-13 cells with IC50 values are 0.089±0.001 nM and 0.022±0.003 nM, respectively.|Products are for research use only. Not for human use.|