Whilst we could not absolutely rule out the risk that lithium-induced reduction of GLI1 more than longer time study course may be an oblique consequence of SHH and SMO downregulation
As demonstrated in Figure 4A, the mRNA ranges of HHIP, CCND1 and PTCH1 have been markedly decreased, suggesting that the action of Hh pathway was downregulated. 125314-13-8This is consistent with…