Product Name :
Fluphenazine decanoate
Description:
Fluphenazine decanoate is a long-acting phenothiazine neuroleptic that used to treat schizophrenia. Fluphenazine decanoate is also a high and continuous dopamine D2 receptor blocker.
CAS:
5002-47-1
Molecular Weight:
591.77
Formula:
C32H44F3N3O2S
Chemical Name:
2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethyl decanoate
Smiles :
CCCCCCCCCC(=O)OCCN1CCN(CCCN2C3=CC(=CC=C3SC3C=CC=CC2=3)C(F)(F)F)CC1
InChiKey:
VIQCGTZFEYDQMR-UHFFFAOYSA-N
InChi :
InChI=1S/C32H44F3N3O2S/c1-2-3-4-5-6-7-8-14-31(39)40-24-23-37-21-19-36(20-22-37)17-11-18-38-27-12-9-10-13-29(27)41-30-16-15-26(25-28(30)38)32(33,34)35/h9-10,12-13,15-16,25H,2-8,11,14,17-24H2,1H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Fluphenazine decanoate is a long-acting phenothiazine neuroleptic that used to treat schizophrenia. Fluphenazine decanoate is also a high and continuous dopamine D2 receptor blocker.|Product information|CAS Number: 5002-47-1|Molecular Weight: 591.77|Formula: C32H44F3N3O2S|Chemical Name: 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethyl decanoate|Smiles: CCCCCCCCCC(=O)OCCN1CCN(CCCN2C3=CC(=CC=C3SC3C=CC=CC2=3)C(F)(F)F)CC1|InChiKey: VIQCGTZFEYDQMR-UHFFFAOYSA-N|InChi: InChI=1S/C32H44F3N3O2S/c1-2-3-4-5-6-7-8-14-31(39)40-24-23-37-21-19-36(20-22-37)17-11-18-38-27-12-9-10-13-29(27)41-30-16-15-26(25-28(30)38)32(33,34)35/h9-10,12-13,15-16,25H,2-8,11,14,17-24H2,1H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 125 mg/mL (211.{{Abatacept} medchemexpress|{Abatacept} Immunology/Inflammation|{Abatacept} Protocol|{Abatacept} Description|{Abatacept} supplier|{Abatacept} Autophagy} 23 mM; Need ultrasonic).{{Edoxaban} medchemexpress|{Edoxaban} Factor Xa|{Edoxaban} Purity & Documentation|{Edoxaban} In Vitro|{Edoxaban} supplier|{Edoxaban} Epigenetic Reader Domain} |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:24513027 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|Six female Persian onagers (Equus hemionus onager) are treated with Fluphenazine decanoate (0.1 mg/kg IM) or saline control. Urinary cortisol, progesterone, estrogen metabolites and behavior are monitored, and follicular dynamics are examined using ultrasonography until ovulation. Onagers demonstrate significantly lower cortisol concentrations when treated with Fluphenazine decanoate (6.61 ng/mg creatinine) compared to saline (9.73 ng/mg creatinine). There are no differences in peak estrogen or progesterone concentrations between the two groups, and all animals ovulate within the expected time frame following Fluphenazine decanoate treatment. However, some onagers exhibit only minor reductions in cortisol secretion and one treated female demonstrates a suppressed luteal progesterone peak, indicating a possible reproductive cost to Fluphenazine decanoate administration.|Products are for research use only. Not for human use.|