Product Name :
Bisindolylmaleimide IV
Description:
Bisindolylmaleimide IV is an inhibitor of pyruvate phosphate dikinase (PPDK).
CAS:
119139-23-0
Molecular Weight:
327.34
Formula:
C20H13N3O2
Chemical Name:
3,4-Bis(1H-indol-3-yl)pyrrole-2,5-dione
Smiles :
O=C1NC(=O)C(=C1C1=CNC2=CC=CC=C21)C1=CNC2=CC=CC=C21
InChiKey:
DQYBRTASHMYDJG-UHFFFAOYSA-N
InChi :
InChI=1S/C20H13N3O2/c24-19-17(13-9-21-15-7-3-1-5-11(13)15)18(20(25)23-19)14-10-22-16-8-4-2-6-12(14)16/h1-10,21-22H,(H,23,24,25)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Bisindolylmaleimide IV is an inhibitor of pyruvate phosphate dikinase (PPDK).|Product information|CAS Number: 119139-23-0|Molecular Weight: 327.34|Formula: C20H13N3O2|Chemical Name: 3,4-Bis(1H-indol-3-yl)pyrrole-2,5-dione|Smiles: O=C1NC(=O)C(=C1C1=CNC2=CC=CC=C21)C1=CNC2=CC=CC=C21|InChiKey: DQYBRTASHMYDJG-UHFFFAOYSA-N|InChi: InChI=1S/C20H13N3O2/c24-19-17(13-9-21-15-7-3-1-5-11(13)15)18(20(25)23-19)14-10-22-16-8-4-2-6-12(14)16/h1-10,21-22H,(H,23,24,25)|Technical Data|Appearance: Solid Power.{{Crystal Violet} MedChemExpress|{Crystal Violet} Others|{Crystal Violet} Protocol|{Crystal Violet} References|{Crystal Violet} custom synthesis|{Crystal Violet} Epigenetics} |Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Adefovir dipivoxil} web|{Adefovir dipivoxil} Orthopoxvirus|{Adefovir dipivoxil} Technical Information|{Adefovir dipivoxil} In Vitro|{Adefovir dipivoxil} custom synthesis|{Adefovir dipivoxil} Autophagy} |Shelf Life: ≥12 months if stored properly.PMID:23539298 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined.|HS Tariff Code: 382200|How to use|In Vitro:|Bisindolylmaleimide IV (Arcyriarubin A) inhibits PKC with an IC50 of 0.1 μM in 1 % DMSO, while the IC50 of 0.55 μM in 10 % DMSO.|References:|Minges A, Groth G. Small-molecule inhibition of pyruvate phosphate dikinase targeting the nucleotide binding site. PLoS One. 2017 Jul 10;12(7):e0181139. doi: 10.1371/journal.pone.0181139. eCollection 2017. PubMed PMID: 28700696; PubMed Central PMCID: PMC5507339.Products are for research use only. Not for human use.|