Product Name :
Alvimopan
Description:
Alvimopan, also known as HSDB-7704 and LY246736, is a drug which behaves as a peripherally acting μ-opioid antagonist. With limited ability to cross the blood–brain barrier, many of the undesirable side-effects of the opioid agonists such as constipation are minimized without affecting analgesia or precipitating withdrawal. It was approved in 2008. Alvimopan is indicated in people to avoid postoperative ileus following partial large or small bowel resection with primary anastomosis. Alvimopan accelerates the gastrointestinal recovery period as defined by time to first bowel movement or flatus.
CAS:
156053-89-3
Molecular Weight:
424.53
Formula:
C25H32N2O4
Chemical Name:
2-[(2S)-2-benzyl-3-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]propanamido]acetic acid
Smiles :
C[C@H]1CN(C[C@H](CC2C=CC=CC=2)C(=O)NCC(O)=O)CC[C@@]1(C)C1=CC(O)=CC=C1
InChiKey:
UPNUIXSCZBYVBB-JVFUWBCBSA-N
InChi :
InChI=1S/C25H32N2O4/c1-18-16-27(12-11-25(18,2)21-9-6-10-22(28)14-21)17-20(24(31)26-15-23(29)30)13-19-7-4-3-5-8-19/h3-10,14,18,20,28H,11-13,15-17H2,1-2H3,(H,26,31)(H,29,30)/t18-,20-,25+/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥360 days if stored properly.{{Guanfacine} medchemexpress|{Guanfacine} Adrenergic Receptor|{Guanfacine} Biological Activity|{Guanfacine} In Vivo|{Guanfacine} custom synthesis|{Guanfacine} Epigenetics}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Alvimopan, also known as HSDB-7704 and LY246736, is a drug which behaves as a peripherally acting μ-opioid antagonist. With limited ability to cross the blood–brain barrier, many of the undesirable side-effects of the opioid agonists such as constipation are minimized without affecting analgesia or precipitating withdrawal. It was approved in 2008. Alvimopan is indicated in people to avoid postoperative ileus following partial large or small bowel resection with primary anastomosis.{{Kynurenic acid} site|{Kynurenic acid} Apoptosis|{Kynurenic acid} Technical Information|{Kynurenic acid} In Vitro|{Kynurenic acid} supplier|{Kynurenic acid} Epigenetic Reader Domain} Alvimopan accelerates the gastrointestinal recovery period as defined by time to first bowel movement or flatus.PMID:24257686 |Product information|CAS Number: 156053-89-3|Molecular Weight: 424.53|Formula: C25H32N2O4|Chemical Name: 2-[(2S)-2-benzyl-3-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]propanamido]acetic acid|Smiles: C[C@H]1CN(C[C@H](CC2C=CC=CC=2)C(=O)NCC(O)=O)CC[C@@]1(C)C1=CC(O)=CC=C1|InChiKey: UPNUIXSCZBYVBB-JVFUWBCBSA-N|InChi: InChI=1S/C25H32N2O4/c1-18-16-27(12-11-25(18,2)21-9-6-10-22(28)14-21)17-20(24(31)26-15-23(29)30)13-19-7-4-3-5-8-19/h3-10,14,18,20,28H,11-13,15-17H2,1-2H3,(H,26,31)(H,29,30)/t18-,20-,25+/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|