Product Name :
Vindesine sulfate

Description:
Vindesine sulfate (Eldesine, Eldisine, Desacetyl Vinblastine amide, Desacetylvinblastine amide, DAVA, DVA, VDS), a vinca alkaloid derived from Catharanthus roseus, is a potent inhibitor of mitosis with antineoplastic activities. Vindesine binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death.

CAS:
59917-39-4

Molecular Weight:
852.00

Formula:
C43H57N5O11S

Chemical Name:
methyl 13-{10-carbamoyl-12-ethyl-10,11-dihydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.0¹,⁹.0²,⁷.0¹⁶,¹⁹]nonadeca-2,4,6,13-tetraen-4-yl}-17-ethyl-17-hydroxy-1,11-diazatetracyclo[13.3.1.0⁴,¹².0⁵,¹⁰]nonadeca-4(12),5,7,9-tetraene-13-carboxylate; sulfuric acid

Smiles :
CN1C2C3(CCN4CC=CC(CC)(C34)C(O)C2(O)C(N)=O)C2=CC(=C(C=C12)OC)C1(CC2CC(O)(CN(C2)CCC2=C1NC1=CC=CC=C21)CC)C(=O)OC.OS(O)(=O)=O

InChiKey:
COFJBSXICYYSKG-UHFFFAOYSA-N

InChi :
InChI=1S/C43H55N5O7.H2O4S/c1-6-39(52)21-25-22-42(38(51)55-5,33-27(13-17-47(23-25)24-39)26-11-8-9-12-30(26)45-33)29-19-28-31(20-32(29)54-4)46(3)35-41(28)15-18-48-16-10-14-40(7-2,34(41)48)36(49)43(35,53)37(44)50;1-5(2,3)4/h8-12,14,19-20,25,34-36,45,49,52-53H,6-7,13,15-18,21-24H2,1-5H3,(H2,44,50);(H2,1,2,3,4)

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Tebentafusp} MedChemExpress|{Tebentafusp} Immunology/Inflammation|{Tebentafusp} Technical Information|{Tebentafusp} Formula|{Tebentafusp} custom synthesis|{Tebentafusp} Autophagy}

Additional information:
Vindesine sulfate (Eldesine, Eldisine, Desacetyl Vinblastine amide, Desacetylvinblastine amide, DAVA, DVA, VDS), a vinca alkaloid derived from Catharanthus roseus, is a potent inhibitor of mitosis with antineoplastic activities.{{Phalloidin} MedChemExpress|{Phalloidin} {Fluorescent Dye}|{Phalloidin} Technical Information|{Phalloidin} In Vitro|{Phalloidin} supplier|{Phalloidin} Autophagy} Vindesine binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death.|Product information|CAS Number: 59917-39-4|Molecular Weight: 852.00|Formula: C43H57N5O11S|Chemical Name: methyl 13-{10-carbamoyl-12-ethyl-10,11-dihydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.0¹,⁹.0²,⁷.0¹⁶,¹⁹]nonadeca-2,4,6,13-tetraen-4-yl}-17-ethyl-17-hydroxy-1,11-diazatetracyclo[13.3.1.0⁴,¹².0⁵,¹⁰]nonadeca-4(12),5,7,9-tetraene-13-carboxylate; sulfuric acid|Smiles: CN1C2C3(CCN4CC=CC(CC)(C34)C(O)C2(O)C(N)=O)C2=CC(=C(C=C12)OC)C1(CC2CC(O)(CN(C2)CCC2=C1NC1=CC=CC=C21)CC)C(=O)OC.OS(O)(=O)=O|InChiKey: COFJBSXICYYSKG-UHFFFAOYSA-N|InChi: InChI=1S/C43H55N5O7.PMID:23671446 H2O4S/c1-6-39(52)21-25-22-42(38(51)55-5,33-27(13-17-47(23-25)24-39)26-11-8-9-12-30(26)45-33)29-19-28-31(20-32(29)54-4)46(3)35-41(28)15-18-48-16-10-14-40(7-2,34(41)48)36(49)43(35,53)37(44)50;1-5(2,3)4/h8-12,14,19-20,25,34-36,45,49,52-53H,6-7,13,15-18,21-24H2,1-5H3,(H2,44,50);(H2,1,2,3,4)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Solubility (25°C).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

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