Product Name :
Disopyramide
Description:
Disopyramide (Dicorantil) is a class IA antiarrhythmic drug with efficacy in ventricular and atrial arrhythmias. Disopyramide blocks the fast inward sodium current of cardiac muscle and prolongs the duration of cardiac action potentials. Disopyramide inhibits HERG encoded potassium channels. Disopyramide also exhibits complex protein binding, and has a potent negative inotropic action.
CAS:
3737-09-5
Molecular Weight:
339.47
Formula:
C21H29N3O
Chemical Name:
4-[bis(propan-2-yl)amino]-2-phenyl-2-(pyridin-2-yl)butanamide
Smiles :
CC(C)N(CCC(C(N)=O)(C1=CC=CC=N1)C1C=CC=CC=1)C(C)C
InChiKey:
UVTNFZQICZKOEM-UHFFFAOYSA-N
InChi :
InChI=1S/C21H29N3O/c1-16(2)24(17(3)4)15-13-21(20(22)25,18-10-6-5-7-11-18)19-12-8-9-14-23-19/h5-12,14,16-17H,13,15H2,1-4H3,(H2,22,25)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Romidepsin} site|{Romidepsin} Epigenetics|{Romidepsin} Technical Information|{Romidepsin} Formula|{Romidepsin} supplier|{Romidepsin} Cancer}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Disopyramide (Dicorantil) is a class IA antiarrhythmic drug with efficacy in ventricular and atrial arrhythmias. Disopyramide blocks the fast inward sodium current of cardiac muscle and prolongs the duration of cardiac action potentials. Disopyramide inhibits HERG encoded potassium channels. Disopyramide also exhibits complex protein binding, and has a potent negative inotropic action.|Product information|CAS Number: 3737-09-5|Molecular Weight: 339.47|Formula: C21H29N3O|Chemical Name: 4-[bis(propan-2-yl)amino]-2-phenyl-2-(pyridin-2-yl)butanamide|Smiles: CC(C)N(CCC(C(N)=O)(C1=CC=CC=N1)C1C=CC=CC=1)C(C)C|InChiKey: UVTNFZQICZKOEM-UHFFFAOYSA-N|InChi: InChI=1S/C21H29N3O/c1-16(2)24(17(3)4)15-13-21(20(22)25,18-10-6-5-7-11-18)19-12-8-9-14-23-19/h5-12,14,16-17H,13,15H2,1-4H3,(H2,22,25)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : ≥ 250 mg/mL (736.{{Hyaluronic acid} medchemexpress|{Hyaluronic acid} Bacterial|{Hyaluronic acid} Technical Information|{Hyaluronic acid} References|{Hyaluronic acid} manufacturer|{Hyaluronic acid} Autophagy} 44 mM).PMID:35567400 |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|HERG tail currents recorded at -40 mV following test pulses to +30 mV were inhibited in a dose-dependent fashion by Disopyramide concentrations within the clinical range (IC50=7.23 μM).|Products are for research use only. Not for human use.|